The pathogenesis of cardiac fibrosis
نویسندگان
چکیده
منابع مشابه
Pathogenesis of liver fibrosis.
1. Liver fibrosis is a common sequel to diverse liver injuries. It is characterized by an accumulation of interstitial collagens and other matrix components. The hepatic stellate cell is pivotal to the pathogenic process. Fibrotic liver injury results in activation of the hepatic stellate cell which undergoes a phenotypic change to a proliferative myofibroblast-like cell which synthesizes exces...
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Submandibular saliva collected from cystic fibrosis patients and control subjects was separated by centrifugation into an insoluble deposit and a clear supernatant. The resulting calcium and phosphorus analyses performed on both fractions warranted a closer investigation as a consistent Ca/P molar ratio of 1.5 was found in the deposit of the cystic fibrosis patients, while no consistent ratio >...
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introduction cardiac hydatid cysts are rare and represent less than 2% of all hydatid cases. they can occur as part of a widespread systemic infection or an isolated event. case presentation here, we presented a case of cardiac hydatid cyst in interventricular septum. conclusions the case presented had some findings that suggested the specific diagnosis of hydatid cyst.
متن کاملCardiac Fibrosis
Heart failure, the clinical manifestation of numerous forms of cardiovascular disease, is a devastating disorder characterized by interstitial fibrosis, chamber remodeling, and reduced ventricular compliance. Heart disease remains the predominant cause of mortality in the United States, accounting for nearly 800 000 deaths per year. Furthermore, it presents a considerable economic burden, with ...
متن کاملThe effect of aerobic exercise on MMP-2 / miR-21 signaling pathway of cardiac fibrosis in elderly rats
Background :The concept of survival has changed since the twentieth century to guarantee quality of life in the twenty-first century (1). Aging is associated with a certain degree of interstitial fibrosis, which progresses to heart failure. Therefore, finding new and practical methods is an important and necessary help to reduce heart tissue fibrosis in the elderly (2). Providing mechanisms by ...
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ژورنال
عنوان ژورنال: Cellular and Molecular Life Sciences
سال: 2013
ISSN: 1420-682X,1420-9071
DOI: 10.1007/s00018-013-1349-6